Spiderman is playing with his Spider-baby toy when Deadpool sneaks up behind him and hits him with a ball. After Spiderman is knocked out, Deadpool drags him away to the laboratory. In his lab, Deadpool prepares to transform Spiderman by throwing a sheet over him. He then pulls out his tools and begins to work on his patient. He starts with his sword and saws through Spiderman's body. Next, he uses a gardening tool to straighten out his patient's body. While looking through his tools, he finds his Minecraft sword which he decides to throw away because he doesn't need it. Finally, he finds a saw which he uses to cut through Spiderman's body. He also dumps a large bucket of balls on Spiderman. After he's finally ready, he lifts the sheet and Spiderman has morphed into the Frankenstein monster!
Deadpool gets excited but Frankenstein won't wake up. He tries to bring Frankenstein to life by hitting him in the head with a shovel. While showing some signs of life, he doesn't wake up completely. Deadpool decides to hit him in the chest to wake him up, and Frankenstein gets up and walks away! While Anna and Minnie Mouse are playing catch, Frankenstein sneaks up on them and they run away. Minnie and Anna split up and run in different directions and the Frankenstein monster decides to chase Minnie Mouse. Minnie finds a house and cries for help as Frankenstein is catching up to her. After an eternity of knocking and screaming for help, Chase finally opens the door and lets her in. While Frankenstein tries to get into the house, Chase and Minnie come up with a plan to get away. After a while, the Frankenstein monster decides to give up opening the door and strolls away. Minnie opens the door and lures him back into the house before he gets too far away. After getting inside, Minnie tricks him into walking up the stairs, and that's when she drops a huge bucket of balls on him! Suddenly Chase brings a rope and ties him up, and both Chase and Minnie run as far away as they can!
Meanwhile, Deadpool is taking a walk when he sees his creation, Frankenstein, tied up on the stairs. He pulls out his wand, casts a spell on Frankenstein, and runs away before anyone sees him. After the spell takes effect, Frankenstein turns back into Spiderman and he unties himself. Once he's able to break free of his bonds, he shrugs off his strange experience and walks away